<ArticleSet>
<Article>
<Journal>
<PublisherName>Pharmaceutical and Biological Evaluations</PublisherName>
<JournalTitle>Pharmaceutical and Biological Evaluations</JournalTitle>
<Issn>2394-0859</Issn>
<Volume>4</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2017</Year>
<Month>06</Month>
<Day>01</Day>
</PubDate>
</Journal>
<ArticleTitle>Analytical method validation for estimation of avanafil and dapoxetine hydrochloride tablet dosage form by HPTLC method</ArticleTitle>
<FirstPage>171</FirstPage>
<LastPage>179</LastPage>
<Language>EN</Language>
<AuthorList>
<Author>
<FirstName>Dhwani</FirstName>
<MiddleName>A.</MiddleName>
<LastName>Shah</LastName>
<Affiliation>Sharda School of Pharmacy, Gandhinagar, Pethapur, Gujarat. shahdhwani57@gmail.com</Affiliation>
</Author>
<Author>
<FirstName>Kunjal</FirstName>
<MiddleName>L.</MiddleName>
<LastName>Vegad</LastName>
</Author>
<Author>
<FirstName>Ekta</FirstName>
<MiddleName>D.</MiddleName>
<LastName>Patel</LastName>
</Author>
<Author>
<FirstName>Hitesh</FirstName>
<MiddleName>K.</MiddleName>
<LastName>Prajapati</LastName>
</Author>
<Author>
<FirstName>Ronak</FirstName>
<MiddleName>N.</MiddleName>
<LastName>Patel</LastName>
</Author>
<Author>
<FirstName>Yogesh</FirstName>
<MiddleName>K.</MiddleName>
<LastName>Patel</LastName>
</Author>
</AuthorList>
<History>
<PubDate>
<Year>2017</Year>
<Month>05</Month>
<Day>02</Day>
</PubDate>
<PubDate>
<Year>2017</Year>
<Month>05</Month>
<Day>23</Day>
</PubDate>
</History>
<Abstract>Objective: A simple, specific, accurate and precise RP-HPTLC method has been developed and validated for simultaneous estimation of Avanafil and Dapoxetine.Methods: The chromatographic separation was achieved on Aluminium plates precoated with Silica gel 60 F254 using chloroform: methanol: ethyl acetate: glacial acetic acid (5:2:3:0.2, v/v/v/v) as mobile phase detected at 279 nm.Results: The correlation coefficient for RP-HPLC method was found to be 0.9987 for Avanafil and 0.9991 Dapoxetine and the linearity range was found to be 1040-3640 ng*spot-1 for Avanafil and 80-280 ng*spot-1 for Dapoxetine.Conclusions: The developed method was successfully applied to marketed tablet dosage form and the results were found with higher confidence.</Abstract>
<ObjectList>
<Object>
<Param>Avanafil, Dapoxetine, RP-HPTLC, Validation</Param>
</Object>
</ObjectList>
<URLs>

Abstract

<Fulltext>
<pdf>http://onlinepbe.com/index.php/PBE/article/view/244/pdf</pdf>
</Fulltext>
</URLs>
</Article>
</ArticleSet>




Copyright (c) 2017 Pharmaceutical and Biological Evaluations

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.



Creative Commons License

 

© Copyright 2017 - Pharmaceutical and Biological Evaluations